מילות מפתח: Breast Carcinoma in Situ (BCIS), Non-Smoking Women, Lung Cancer Risk, Colorectal Cancer Risk, Cancer Screening

רקע מדעי ומטרה:

Introduction: Breast carcinoma in situ (BCIS) is a non-invasive stage of breast cancer with a generally favorable prognosis. BCIS have a high survival rate, with a 10-year breast cancer-specific survival rate of 97-98%. This promising prognosis underscores the importance of tailored screening and preventive strategies in family medicine.
Goal: Examining the risk of developing lung or colorectal malignancy among non-smoking

שיטות:

Methods: Retrospective Case Control study. The database includes patient demographic and clinical characteristics, hospital and outpatient clinical diagnoses of malignancies between from 1/1/2006 to 31/12/2023. Study population- Non-smokers females above the age of 40 with no history of malignancy (1,010,000).

תוצאות:

Results: Women who have been diagnosed with BCIS have a 2.6-fold increased risk of developing Lung Cancer. Women who have been diagnosed with BCIS have a 0.5 reduced risk of developing colon cancer. The risk of Breast Carcinoma in situ is the same for Jewish and Arab women. Colon cancer risk is twice as high in Jewish women with a history of BCIS compared to Arab women with the same history.

מסקנות:

Conclusion: These findings highlight the importance of continued surveillance and targeted prevention strategies for women with a history of BCIS. The increased risk of lung cancer underscores the need for careful monitoring, while the reduced risk of colorectal cancer suggests that standard screening guidelines may be appropriate for this population.

חשיבות לרפואת המשפחה:

Tailored screening and preventive strategies in family medicine.